When should methotrexate and leflunomide be stopped in a patient with decreasing white cell count and active diverticulitis infection?

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Authors: Tripdatabase
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Abstract

Methotrexate and leflunomide should be stopped in cases of decreasing white cell count and active diverticulitis infection, according to safety guidelines on drug-induced myelosuppression and infection risk.

Fields of Study & Subjects

Rheumatoid Arthritis Research and Therapies Diverticular Disease and Complications Pharmacovigilance and Adverse Drug Reactions

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
10 February 2026
Language
EN