irinatu/shape_diff: First public release

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: irinatu
DOI: 10.5281/zenodo.18589150
Cited by: 0

Abstract

This script compares two RNA SHAPE(-MaP) reactivity profiles provided in `.map` format (e.g. *in vitro* vs *in cellulo*) and identifies regions with significantly different reactivities. The method is described by Smola et al. (In-cell RNA structure probing with SHAPE-MaP. Nature Protocols 2018 13:6, 13, 1181–1195.)

Fields of Study & Subjects

RNA and protein synthesis mechanisms RNA Research and Splicing RNA regulation and disease

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
10 February 2026
Language
EN