Conceptual Design of a Closed-Loop Biohybrid Neural Interface for Functional Recovery in Partial Spinal Cord Injury

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Authors: NAITIK Valecha
Cited by: 0

Abstract

This work presents a conceptual bioengineering framework for a closed-loop biohybrid neural interface designed to support functional recovery in cases of partial spinal cord injury. The proposed system combines neural signal acquisition, electronic processing, targeted stimulation below the injury site, and biologically compatible support structures to create a functional communication bridge across damaged neural regions. The concept explores how electronic neural bypass systems may assist in restoring limited motor control by transmitting brain signals around partially disrupted spinal pathways while enabling adaptive feedback through closed-loop control. The paper also discusses the fundamental differences between structural orthopedic replacement and neural communication restoration, highlighting why spinal injuries require hybrid neuroengineering approaches rather than purely mechanical solutions. Engineering challenges, biological constraints, and ethical considerations are examined, including limitations in neural decoding accuracy, long-term implant compatibility, and realistic clinical applicability. The framework is theoretical and intended to stimulate discussion and further research into interdisciplinary biohybrid neural technologies. This work represents an independent conceptual design and does not include experimental validation, clinical testing, or claims of medical effectiveness.

Fields of Study & Subjects

Neuroscience and Neural Engineering Spinal Cord Injury Research EEG and Brain-Computer Interfaces

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
11 February 2026
Language
EN
Document type
Preprint