What are the cellular and molecular mechanisms responsible for methylphenidate-induced cardiotoxicity?

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Tripdatabase
DOI: 10.5281/zenodo.18621073
Cited by: 0

Abstract

Methylphenidate-induced cardiotoxicity involves increased oxidative stress, catecholamine elevation, and impaired energy metabolism, leading to cardiomyocyte damage. Animal studies suggest potential protective effects of ATP and melatonin, but human data are needed.

Fields of Study & Subjects

Cardiac electrophysiology and arrhythmias Takotsubo Cardiomyopathy and Associated Phenomena Attention Deficit Hyperactivity Disorder

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
12 February 2026
Language
EN