LINC-ROR and a TCF ncRNA, TUNAR, are important non-coding components of TE lineage specification in human embryonic stem cells.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of LINC-ROR and a TCF ncRNA, TUNAR as lineage commitment factors in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Developmental Biology and Gene Regulation
Pluripotent Stem Cells Research
Cancer-related molecular mechanisms research
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 12 February 2026
- Language
- EN
- Document type
- Preprint