Metalloproteinases of the ADAMTS family are components of the TE differentiation program in an iPS model of lineage specification in the human embryo.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here identification of metalloproteinases of the ADAMTS family as lineage commitment cooperating factors in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Protease and Inhibitor Mechanisms
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 12 February 2026
- Language
- EN
- Document type
- Preprint