Retinoid acid signaling during lineage commitment in the human embryo to the trophectoderm (TE).
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here identification of a requirement for retinoid acid signaling in lineage commitment in embryonic stem cells of the human embryo. This included important changes in Rai14 and Stra16.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Reproductive Biology and Fertility
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 12 February 2026
- Language
- EN
- Document type
- Preprint