PDE4B in embryonic stem cells and the trophectoderm.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of PDE4B as a lineage commitment factor or lineage commitment cooperating factor in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Phosphodiesterase function and regulation
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 12 February 2026
- Language
- EN
- Document type
- Preprint