Transporter composition alterations during lineage commitment in pluripotent stem cells.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here identification and characterization of key changes in transporter composition during lineage commitment in embryonic stem cells of the human embryo. Transporter composition alteration during lineage commitment in pluripotent stem cells alluded to basic changes in ionic context associated with pluripotency and nutritional requirements in the trophectoderm.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Reproductive Biology and Fertility
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 12 February 2026
- Language
- EN
- Document type
- Preprint