PPARG expression change is associated with trophectoderm specification in embryonic stem cells.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of PPARG as a lineage commitment factor in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Peroxisome Proliferator-Activated Receptors
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 13 February 2026
- Language
- EN
- Document type
- Preprint