CYCLOSPORIN - A DEPENDENT EFFECT OF PLANTAGO MAJOR L. POLYPHENOLS ON LIVER MITOCHONDRIAL MEGAPORE

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Khamida Sayfiyeva
DOI: 10.5281/zenodo.18641648
Cited by: 0

Abstract

The pathological opening of the mitochondrial permeability transition pore (mPTP) leads to cell death. This study investigated the effects of glucopyr-T and xylopyr-T polyphenolic compounds isolated from Plantago major L. on the mPTP of rat liver mitochondria in a cyclosporin A–dependent manner. The results indicate that these compounds are promising modulators of mPTP activity.

Fields of Study & Subjects

Mitochondrial Function and Pathology Cell death mechanisms and regulation Cardiac Ischemia and Reperfusion

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
14 February 2026
Language
EN