POLI as a component of the TE specification program.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18651715
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of POLI as a lineage commitment factor or lineage commitment cooperating factor in embryonic stem cells of the human embryo.

Fields of Study & Subjects

Pluripotent Stem Cells Research Developmental Biology and Gene Regulation Epigenetics and DNA Methylation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
15 February 2026
Language
EN
Document type
Preprint