LRP1b and LRP8 function in lineage commitment in the human embryo.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of LRP1b and LRP8 as lineage commitment markers or lineage commitment cooperating factor in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Reproductive Biology and Fertility
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 16 February 2026
- Language
- EN
- Document type
- Preprint