Oligodendrocyte and myelin program genes associated with lineage commitment to the TE in humans.

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Authors: Shahan Mamoor
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of oligodendrocyte and myelin program genes associated with lineage commitment to the TE in humans. The TE myelin program included MAG, Nsmaf, Smpdl3a/b, Oligophrenin and a non-coding RNA, OLMALINC.

Fields of Study & Subjects

Developmental Biology and Gene Regulation Pluripotent Stem Cells Research Neurogenesis and neuroplasticity mechanisms

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
16 February 2026
Language
EN
Document type
Preprint