Oligodendrocyte and myelin program genes associated with lineage commitment to the TE in humans.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of oligodendrocyte and myelin program genes associated with lineage commitment to the TE in humans. The TE myelin program included MAG, Nsmaf, Smpdl3a/b, Oligophrenin and a non-coding RNA, OLMALINC.
Fields of Study & Subjects
Developmental Biology and Gene Regulation
Pluripotent Stem Cells Research
Neurogenesis and neuroplasticity mechanisms
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 16 February 2026
- Language
- EN
- Document type
- Preprint