PPARA with PPARG functions in lineage commitment in the human embryo.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18669013
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of PPARA and PPARG as lineage commitment factors or lineage commitment cooperating factors in embryonic stem cells of the human embryo.

Fields of Study & Subjects

Pluripotent Stem Cells Research Peroxisome Proliferator-Activated Receptors Developmental Biology and Gene Regulation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
17 February 2026
Language
EN
Document type
Preprint