Differential kinase and phosphatase requirements during fate choice in embryonic stem cells.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18669021
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here differential kinase and phosphatase requirements during fate choice in embryonic stem cells. Among the kinases and phosphatases identified as critical for the embryonic stem cell included Ppp1r17, Dusp4 and Dusp5, Acp2 and Aclp3, and Map3k21.

Fields of Study & Subjects

Pluripotent Stem Cells Research Developmental Biology and Gene Regulation Reproductive Biology and Fertility

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
17 February 2026
Language
EN
Document type
Preprint