Redox biology of the cell and the molecules that regulate cellular redox are components of the TE specification program from pluripotent stem cells in the human embryo.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe cardinal changes in redox biology of the cell and the molecules that regulate cellular redox as components of lineage commitment in embryonic stem cells of the human embryo. This included changes in Txnip, Prxl2a and Chac1.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Redox biology and oxidative stress
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 17 February 2026
- Language
- EN
- Document type
- Preprint