Structural Necessity of a Temporal Reconciliation Parameter (Δt) in Immune-Inflamed Pancreatic Adenocarcinoma
Abstract
Version 2.33. This study analyzes TCGA-PAAD transcriptomic data to evaluate structural coexistence of NK cytotoxic readiness and CD39-centered suppressive signaling. The framework introduces Δt as a theoretical reconciliation parameter rather than a measured temporal interval. This version includes correlation coefficients, survival statistics, stage analysis, limitations, and falsifiability statement.
Fields of Study & Subjects
Cancer Immunotherapy and Biomarkers
Pancreatic and Hepatic Oncology Research
Single-cell and spatial transcriptomics
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 23 February 2026
- Document type
- Preprint