Towards improved anticancer properties of the G-quadruplex-forming T40231 aptamer through increased flexibility of nucleoside residues
Abstract
Raw data and data accompanying publication:Kotkowiak W., Bartyś N., Pasternak A. (2025) Towards improved anticancer properties of the G-quadruplexforming T40231 aptamer through increased flexibility of nucleoside residues. Sci. Rep. 15: 25159. Authors: Weronika Kotkowiak (1), Natalia Bartyś (1), Anna Pasternak (1)Affiliation: (1) Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznan, Poland.* Corresponding author: e-mail: apa@ibch.poznan.plThis study was supported by National Science Centre, Poland grants: 020/37/B/NZ7/02008 to A.P., 2021/41/B/NZ7/03910 to W.K., 2024/08/X/ST4/00521 to N.B.Contents:(1)Serum stability data(2)Thermal stability data(3)Native gel high-resolution image file(4)Circular dichroism data(5)qPCR data(6)Antiproliferative assay data
Fields of Study & Subjects
DNA and Nucleic Acid Chemistry
Advanced biosensing and bioanalysis techniques
RNA Interference and Gene Delivery
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 23 February 2026
- Language
- EN
- Document type
- Dataset