THE ANTITUMOR EFFICACY OF SESAMIN IN MCF-7 BREAST CANCER CELLS: THE MODULATORY ROLE OF MG132
Abstract
Breast cancer remains one of the leading causes of malignancy-related mortality globally. Sesamin, a major lignan found in sesame oil, has garnered significant attention for its potent antioxidant, anti-inflammatory, and pro-apoptotic properties. This study evaluates the impact of Sesamin on the MCF-7 (estrogen receptor-positive) human breast cancer cell line and investigates how the proteasome inhibitor MG132 influences these effects.
Fields of Study & Subjects
Sesame and Sesamin Research
Plant-derived Lignans Synthesis and Bioactivity
Nigella sativa pharmacological applications
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 24 February 2026
- Language
- EN
- Document type
- Dataset