METABOLIC PROFILING OF PERIPHERAL MONOCYTES AS A DIAGNOSTIC TOOL FOR COMMUNITY ACQUIRED PNEUMONIA IN INFANTS WITH CONGENITAL HEART DEFECTS

Zenodo (CERN European Organization for Nuclear Research) 2026 Dataset Open access

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Authors: Mukhammadkhonov Abdulfaizkhon Shamsuddinkhon ugli, Worldy Knovledge Publishing Centre
DOI: 10.5281/zenodo.18760409
Cited by: 0

Abstract

Respiratory infections remain a significant cause of infant mortality and morbidity worldwide. The clinical management of community-acquired pneumonia becomes particularly complex when it occurs alongside congenital heart defects. These cardiac anomalies disrupt normal blood flow and oxygenation, creating a challenging environment for the immune system. Understanding how immune cells like monocytes adapt or fail at a metabolic level during this combined pathology is crucial for developing more precise diagnostic and therapeutic strategies for vulnerable pediatric patients.

Fields of Study & Subjects

Pneumonia and Respiratory Infections Sepsis Diagnosis and Treatment Congenital Heart Disease Studies

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
24 February 2026
Language
EN
Document type
Dataset