Spectravax: computational design of broad-spectrum T-cell-inducing vaccines

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Authors: Phil Palmer, Sneha Vishwanath
Cited by: 0

Abstract

Spectravax is a computational framework for designing broad-spectrum vaccines that optimise both pathogen conservation and host HLA coverage. It integrates epitope prediction, sequence clustering, and coverage optimisation to generate vaccine antigen candidates targeting T-cell responses. For reference data required to run the pipeline, see: https://doi.org/10.5281/zenodo.18761002 Full documentation and usage examples are available in the repository README.

Fields of Study & Subjects

vaccines and immunoinformatics approaches Immunotherapy and Immune Responses Chemical Synthesis and Analysis

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
24 February 2026
Language
EN