Is there a causal relationship between extended use of antihistamines and dementia?

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Tripdatabase
DOI: 10.5281/zenodo.18764776
Cited by: 0

Abstract

The evidence suggests a potential association between long-term use of antihistamines with strong anticholinergic effects and an increased risk of dementia, but definitive causation has not been established.

Fields of Study & Subjects

Pharmaceutical Practices and Patient Outcomes Dementia and Cognitive Impairment Research Cholinesterase and Neurodegenerative Diseases

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
25 February 2026
Language
EN