Single-Cell Signatures of EBV-Associated Immune Scarring in Systemic Sclerosis B Cells

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Authors: Ritschel Glen
Cited by: 0

Abstract

Manuscript submitted to Biology (MDPI) on February 25, 2026 (Manuscript ID: biology-4198518). This version analyzes single-cell RNA-seq data from systemic sclerosis patient PBMCs (GSE195452), demonstrating EBV-associated immune scarring in B cells and identifying BTK inhibitors as therapeutic candidates. Related code repository: https://doi.org/10.5281/zenodo.18778992

Fields of Study & Subjects

Systemic Sclerosis and Related Diseases Viral-associated cancers and disorders T-cell and B-cell Immunology

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
26 February 2026
Language
EN
Document type
Preprint