Single-Cell Signatures of EBV-Associated Immune Scarring in Systemic Sclerosis B Cells
Abstract
Manuscript submitted to Biology (MDPI) on February 25, 2026 (Manuscript ID: biology-4198518). This version analyzes single-cell RNA-seq data from systemic sclerosis patient PBMCs (GSE195452), demonstrating EBV-associated immune scarring in B cells and identifying BTK inhibitors as therapeutic candidates. Related code repository: https://doi.org/10.5281/zenodo.18778992
Fields of Study & Subjects
Systemic Sclerosis and Related Diseases
Viral-associated cancers and disorders
T-cell and B-cell Immunology
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 26 February 2026
- Language
- EN
- Document type
- Preprint