broadinstitute/bican-mccarroll-manuscript1: Initial release of BICAN manuscript code
Abstract
Initial Release of BICAN Analysis Code This is the first public release of code supporting the McCarroll BICAN manuscript (2026). It captures the analytical state of the project at this milestone and serves as a stable reference point for the results presented in the manuscript. This release includes the primary analytical workflows implemented as dedicated R packages, providing support for: Differential expression analysis eQTL analysis Donor age prediction from gene expression data Together, these components constitute the core analytical pipelines underlying the manuscript. In addition, this release includes the bican.mccarroll.figures package, which reproduces the main and supplemental figures presented in the manuscript using the outputs generated by the analytical workflows described above. This release is versioned pre-1.0 and reflects an analysis snapshot associated with manuscript preparation. Interfaces and implementation details may evolve prior to final submission and the 1.0 release. Additional analytical components are under active development and will be incorporated in subsequent minor releases prior to the 1.0 manuscript submission release.
Fields of Study & Subjects
Gene expression and cancer classification
Genetic Associations and Epidemiology
Single-cell and spatial transcriptomics
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 26 February 2026
- Language
- EN