Oral Dispersible Tablet: Technologies, Challenges and Future Perspectives

Oral route of drug administration is the most common route of drug administration. Oral dispersible tablet producing beneficial effects among Novel oral drug delivery system because they improved patient compliance and have more beneficial advantages from other oral dosage formulations. They are also solid dosage forms that break down in the mouth, when saliva is present because of super disintegrates in the formulation. Consequently, this method of drug delivery facilitates effective oral administration for both paediatric and geriatric populations where swallowing can be challenging. Numerous researchers have developed orodispersible tablets using various techniques. The compression method is the most widely used preparation technique. Other specialized methods include molding, melt granulation, phase-transition processes, sublimation, freeze-drying, spray-drying, and the effervescent method. Since these tablets dissolve immediately in the mouth, their taste plays a crucial role. Several strategies have been implemented to mask the unpleasant taste of the drug. From all other dosage for they are also evaluated as hardness, friability, wetting time, moisture content, disintegration test and dissolution test.