KIC Spheroid Calcium Pipeline (Script 02b/03) – Multi-Batch Dataset Integration

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Authors: Michele F. Buono, Talitha C. F. Spanjersberg, Nikki Scheen, C.L. van der Wilt
Cited by: 0

Abstract

KIC Spheroid Calcium Pipeline — Script 02b/03 GUI-based R pipeline for merging multiple batch-level merged.csv datasets generated in Script 02a into a unified multi-batch dataset. What's included GUI selection of input/output paths Recursive scanning for merged.csv files Merging of multiple batch-level datasets into a unified multi-batch table Automatic column alignment across batches (NA fill for missing columns) Preservation of logical flags generated in Script 02a (keep_1hz, valid_well) Retention of assigned metadata (Group, optional RowGroup, Batch) Integrity checks for missing metadata and duplicate well identifiers Export of a standardized merged_raw.csv file Inputs merged.csv files generated in Script 02a Nested folder structures supported (recursive search enabled) Required columns: Well Batch Group Num.Peaks Optional but recommended: RowGroup keep_1hz valid_well Outputs merged_raw.csv containing: All standardized MEANS summary statistics Preserved filtering flags Assigned Group Optional RowGroup Batch identifiers Source tracking metadata Dataset is standardized and ready for statistical modeling, cross-group comparisons, multi-batch integration, and downstream visualization (Script 03). Citation Developed by Michele Buono, Talitha Spanjersberg, Nikki Scheen, and Nina van der Wilt.Free for research use and adaptation with citation via Zenodo.

Fields of Study & Subjects

Cell Image Analysis Techniques Research Data Management Practices Scientific Computing and Data Management

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
27 February 2026
Language
EN