DEVELOPMENT AND OPTIMIZATION OF A LIPID-BASED SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) FOR ENHANCING THE LYMPHATIC ABSORPTION AND BIOAVAILABILITY OF SILYMARIN.

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Authors: Dr. Khushboo Arora2 Mr. Swapnil R. Dudhakohar*1
Cited by: 0

Abstract

Background: Silymarin, a potent hepatoprotective agent, suffers from poor aqueous solubility (BCS Class II/IV) and extensive first-pass metabolism, leading to low oral bioavailability (

Fields of Study & Subjects

Drug Solubulity and Delivery Systems Advanced Drug Delivery Systems Proteins in Food Systems

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
1 March 2026
Language
EN