Ambient light drives verteporfin-induced protein cross-linking during standard laboratory sample processing

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Authors: Konstantinos G Baroutis
Cited by: 0

Abstract

This dataset accompanies the manuscript: Ambient light drives verteporfin-induced protein cross-linking during standard laboratory sample processing. Verteporfin (VP), a benzoporphyrin photosensitizer widely used as a pharmacological inhibitor of the YAP–TEAD transcriptional complex, induces high-molecular-weight complex (HMWC) formation, apparent YAP depletion, and cytotoxicity that are predominantly photochemical artifacts arising from ambient light exposure during standard laboratory procedures. This dataset provides all primary data supporting the manuscript conclusions.

Fields of Study & Subjects

Hippo pathway signaling and YAP/TAZ Photodynamic Therapy Research Studies Neonatal Health and Biochemistry

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
8 March 2026
Language
EN
Document type
Dataset