Extended Data Tables (2, 5, 8, 9, 10, 11) for the manuscript: Microbial transcriptional reprogramming defines tumour-restricted antigens from taxonomically overlapping microbiomes

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Authors: Zhang Yuxin, Wang Wei, Zuo Xiao, Chen Tao, Li Kecheng, Zhu Tianyang, Zhang Yuanliang, Yang Huiya, Wang Jialiang, Wei Dandan, Zhang Jianfeng, Cui Jialong
+14 more Wang Lirong, Li Zhilei, Ding Dushan, Sun Ruixia, He Yin, Zhou Yanfei, Ye Chenkun, Chen Dandan, Jiang Long, Lang Xueting, Zhao Qian, Lu Zhang, Wang Hongzhi, Zhang Yuanwei
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Abstract

This dataset contains the large Extended Data Tables (Tables 2, 5, 8, 9, 10, and 11) supporting the manuscript titled "Microbial transcriptional reprogramming defines tumour-restricted antigens from taxonomically overlapping microbiomes". Due to the large file sizes of these specific datasets (e.g., the comprehensive predicted binding affinity matrix in Table 11, and single-cell TCR sequences in Table 8), which exceed the standard submission system limits, they are hosted here to facilitate the peer-review process and ensure data accessibility. Extended Data Table 2 | Taxonomy of the curated tumour microbial reference dataset. Extended Data Table 5 | Peptides identified by immunopeptidomics in tumour sample. Extended Data Table 8 | Single-cell TCR sequences and clonotype annotations. Extended Data Table 9 | Microbial peptides from CRC-associated bacteria. Extended Data Table 10 | T cells annotated with clonal expansion and binding affinity. Extended Data Table 11 | Predicted binding affinity between expanded TCR clonotypes and microbial peptides.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses vaccines and immunoinformatics approaches

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
3 March 2026
Language
EN
Document type
Dataset