Cancer- Pay to Persist

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Authors: James F. Lombardo
Cited by: 0

Abstract

“Cancer reframed as a configuration-space exploit using the Pay-to-Persist framework. Cancer cells found a way to lower metabolic costs (S[γ]), degrade coherent identity (R[γ]), and optimize for cell-level rather than organism-level persistence. Treatment strategy: close the exploits through metabolic targeting, differentiation therapy, and microenvironment normalization rather than just killing cells. Includes novel combination therapies, testable predictions, and clinical classification by exploit profile. Released under CC BY-SA 4.0 with viral open science requirements: any clinical trials, drug development, or commercial applications must publish results openly and share protocols. Cancer treatment must remain a commons.”

Fields of Study & Subjects

Cancer Cells and Metastasis Cancer Hypoxia and Metabolism Mathematical Biology Tumor Growth

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
3 March 2026
Language
EN