What is the significance of the interaction between clopidogrel and omeprazole?

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Tripdatabase
DOI: 10.5281/zenodo.18851606
Cited by: 0

Abstract

The interaction between clopidogrel and omeprazole is significant due to omeprazole's inhibition of CYP2C19, which decreases clopidogrel activation. This can potentially lead to diminished antiplatelet effects and an increased risk of cardiovascular events.

Fields of Study & Subjects

Antiplatelet Therapy and Cardiovascular Diseases Pharmacogenetics and Drug Metabolism Blood Coagulation and Thrombosis Mechanisms

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
3 March 2026
Language
EN