NEUROBIOLOGICAL MECHANISMS OF AUTONOMIC AND PSYCHOSOMATIC DYSREGULATION IN TRIGEMINAL NEURALGIA: MOLECULAR AND CENTRAL SENSITIZATION PERSPECTIVES
Abstract
Trigeminal neuralgia (TN) is a chronic neuropathic pain condition characterized by recurrent, brief episodes of severe, electric shock-like facial pain distributed along one or more branches of the trigeminal nerve. Although traditionally attributed to neurovascular compression and focal demyelination, contemporary research demonstrates that TN represents a complex disorder involving peripheral nerve injury, central sensitization, neuroinflammation, autonomic imbalance, and psychosomatic dysregulation (1,3).
Fields of Study & Subjects
Trigeminal Neuralgia and Treatments
Pain Mechanisms and Treatments
Pain Management and Treatment
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 4 March 2026
- Language
- EN
- Document type
- Dataset