CHANGER Manual for the Method "Iterative Ethics Review" - preliminary version 1.2

Modern research is increasingly complex, often outpacing the traditional "one-and-done" ethics check. This manual introduces a shift from static, ex-ante evaluations toward a dynamic, iterative ethics review process. By moving away from the assumption that all ethical concerns can be captured in a single initial meeting, this methodology prioritizes continuous reflection. It provides a framework that embraces change, ensuring that ethical oversight evolves alongside the research itself. The approach is based on notions of ethics-by-design, continuous reflection, and inspired by agility.