A Study on Diagnostic Values of Peripheral Blood Smear in Different Types of Doshaja Pandu

Loss in the normal colour or discoloration of the body is called Panduta. Along with loss of normal color or discoloration, abnormalities are seen in the texture and luster of the body. Panduroga has been regarded as Agnimandhyakrita rasa dushtijanya pitta pradhanavyadhi (Acharya, 1997), characterized by Panduvaivarnayatai eketakidhulisamanavarna (Sashtri, 2012). Pandu Roga is included under the heading of the Varnopalakshita Roga, i.e., varnapradhanyavyadhi (Chakrapanidatta, 2012). Pitta is responsible for normal body color, but when vitiated, it leads to loss of complexion or panduta. Panduroga is referred to as Vilohita, Harima, and Halima in Vedas, and Susruta named it Panaki, Langaraka, and Kumbawayo (Shastri, 2010). Lakshana (signs and symptoms) are crucial for diagnosis. Samanya lakshana (general symptoms) and vishista lakshana (specific symptoms) indicate dosha involvement. In ancient times, without modern technology, Acharyas relied on keen observation of lakshana. With advancements like peripheral blood smear, changes in RBC morphology can be observed. Though numerous studies exist on Pandu, none have explored morphological changes in different types of Doshaja Pandu Roga. This study aims to find the relevance of morphological changes in peripheral blood smear and observe the scientific basis in various types of Panduroga.