ROLE OF CHOLINERGIC NEUROTRANSMISSION IN COGNITIVE DECLINE ASSOCIATED WITH CHRONIC OBSTRUCTIVE AND CARDIOVASCULAR DISORDERS

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Authors: Sadullaev Dilshod Izbilloevich, Worldy Knovledge Publishing Centre
Cited by: 0

Abstract

Introduction.Cognitive impairment is a common comorbidity in patients with chronic obstructive syndrome (COS) in the presence of cardiovascular pathology (CVD). The main mechanisms include chronic hypoxemia, systemic inflammation, endothelial dysfunction, and imbalance of the autonomic nervous system [1–3,5]. Recent studies indicate that cholinergic dysfunction is a key integrative mechanism linking peripheral pathology with cognitive decline [7,8].

Fields of Study & Subjects

Neurological Disease Mechanisms and Treatments Dementia and Cognitive Impairment Research Chronic Obstructive Pulmonary Disease (COPD) Research

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
5 March 2026
Language
EN
Document type
Dataset