Using The Virtual Brain to probe the effects of senescence-driven alterations in neuronal firing activity on brain dynamics in Alzheimer's disease

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Authors: Cathlin Jiaqi Han, Alex I. Wiesman, Anthony McIntosh
Cited by: 0

Abstract

Poster created for Cognitive Neuroscience Society (CNS) 2026 Annual Meeting. Neuronal senescence is a stressor-induced change in cell state that has been associated with the pathology of Alzheimer's disease. This Sketchpad Series poster presents plans to use the brain simulation platform The Virtual Brain to simulate and examine how changes in neuronal firing activity caused by neuronal senescence might affect local and large-scale brain dynamics in Alzheimer's disease.

Fields of Study & Subjects

Neural dynamics and brain function Alzheimer's disease research and treatments Functional Brain Connectivity Studies

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
5 March 2026
Language
EN