FORMULATION AND EVALUATION OF BUTTERFLY PEA EXTRACT CREAM FOR ANTI-AGING ACTIVITY

Semi-solid dosage forms such as creams are widely used in topical and transdermal drug delivery due to their ease of application, patient compliance, and ability to provide localized as well as sustained therapeutic effects. Among natural ingredients explored for dermatological applications, Clitoria ternatea (family Fabaceae) has gained significant attention for its diverse pharmacological and cosmetic potential. Commonly known as butterfly pea, this perennial leguminous plant is rich in bioactive constituents including anthocyanins, flavonoids, tannins, phenolic compounds, triterpenoids, and glycosides, which contribute to its antioxidant, anti- inflammatory, antimicrobial, antidiabetic, neuroprotective, and nootropic activities. The vivid blue anthocyanins present in its flowers not only serve as natural colorants but also exhibit strong free radical scavenging properties that may protect the skin against oxidative stress and premature aging. Traditional systems of medicine have utilized different parts of the plant for cognitive enhancement, wound healing, and treatment of inflammatory conditions. Recent pharmacological studies further support its therapeutic potential in managing hyperglycemia, microbial infections, and inflammatory disorders. Incorporation of C. ternatea extracts into cream formulations offers a promising approach for developing herbal, skin-protective, and anti-aging topical preparations with enhanced safety and efficacy.