Minimal Amino Acid Alphabet for Protein Design

Zenodo (CERN European Organization for Nuclear Research) 2026 Dataset Open access

Read full text
Authors: Vojtěch Spiwok, Karel Půbal, Kseniia Kushnir, Karolína Loužecká, Vladimír Setnička, Petra Lipovová
DOI: 10.5281/zenodo.18889430
Cited by: 0

Abstract

Proteins are built from 20 canonical amino acids. It is interesting to explore whether proteins can be formed from significantly reduced amino acid alphabets. Our bioinformatics survey of UniProt (more than 250 M sequences) revealed that proteins composed of reduced amino acid alphabets (

Fields of Study & Subjects

Protein Structure and Dynamics RNA and protein synthesis mechanisms Chemical Synthesis and Analysis

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
6 March 2026
Language
EN
Document type
Dataset