SEReM Criteria Manual : Standardized Evidence Reliability Evaluation Metrics ( Version 1.0 )

A structured methodological framework for evaluating the reliability, transparency, and reproducibility of scientific studies using a standardized Evidence Reliability Index (ERI). SEReM (Standardized Evidence Reliability Evaluation Metrics) is a structured methodological framework developed to support the systematic evaluation of the reliability, transparency, and reproducibility of scientific studies. The framework provides a rule-based evaluation system designed to assist researchers in assessing key methodological and reporting characteristics that influence the interpretability and trustworthiness of published evidence. SEReM evaluates studies across five core domains: methodological integrity, transparency and disclosure, scientific governance, reproducibility and verifiability, and research integrity signals. Each domain contains predefined signaling questions that are assessed using standardized response categories. These structured criteria allow evaluators to consistently document methodological features of a study while reducing variability in evidence appraisal. Using predefined scoring rules, SEReM generates a quantitative Evidence Reliability Index (ERI) that summarizes the degree to which a study demonstrates transparent and reproducible research practices. The ERI score is subsequently mapped to standardized reliability bands that provide an interpretable summary of overall evidence reliability. The SEReM framework is intended for use in meta-research, systematic reviews, umbrella reviews, methodological audits, and editorial methodological appraisal. It may also support research training by providing a structured approach to evaluating methodological rigor in scientific literature. SEReM integrates principles from established evidence appraisal and reporting frameworks including the Cochrane Risk of Bias Tool, GRADE, CONSORT, and PRISMA, which informed the design of its evaluation domains and reporting criteria. This repository provides Version 1.0 of the SEReM Criteria Manual, documenting the conceptual framework, domain structure, signaling questions, scoring methodology, and implementation workflow. The framework is intended as a methodological support tool and does not replace established domain-specific risk-of-bias assessments.