HamanoLaboratory/superDIRECTEUR: superDIRECTEUR

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: HamanoLaboratory
DOI: 10.5281/zenodo.18909775
Cited by: 0

Abstract

SuperDIRECTEUR predicts combinations of small molecules by accounting for dynamic molecular mechanistic changes during direct programming induction. To account for these dynamic changes, the cell conversion process is divided into several stages (e.g., Primal stage, Immature stage, and Mature stage). Combinations of small molecules that induce cell conversion between adjacent stages are then predicted.

Fields of Study & Subjects

Pluripotent Stem Cells Research Computational Drug Discovery Methods Gene Regulatory Network Analysis

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
8 March 2026
Language
EN