Pcdh8 silencing during germ layer lineage choice of pluripotent stem cells.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18915716
Cited by: 0

Abstract

The organ systems of the human body are each derived from three germ layers: the endoderm, mesoderm, and ectoderm. We defined here using transcriptomics a minimal set of components required or important for germ layer fate choice to the endoderm in the first trimester of human development. We describe Pcdh8 silencing during germ layer lineage choice of pluripotent stem cells in Homo sapiens.

Fields of Study & Subjects

Pluripotent Stem Cells Research Developmental Biology and Gene Regulation Epigenetics and DNA Methylation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
8 March 2026
Language
EN
Document type
Preprint