FMR1 and DTNA: neurodegeneration-associated machinery possess functions in lineage commitment in the human embryo.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18915869
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We report here that FMR1 and DTNA, neurodegeneration-associated machinery, possess functions in lineage commitment in the human embryo.

Fields of Study & Subjects

Developmental Biology and Gene Regulation Pluripotent Stem Cells Research Epigenetics and DNA Methylation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
8 March 2026
Language
EN
Document type
Preprint