Lmod1 and Lmod2 function in lineage commitment in the human embryo.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of Lmod1 and Lmod2 as lineage commitment factors or lineage commitment cooperating factors in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Epigenetics and DNA Methylation
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 10 March 2026
- Language
- EN
- Document type
- Preprint