Deviations from genetic additivity driven by rare variants at biobank scale

Zenodo (CERN European Organization for Nuclear Research) 2026 Dataset Open access

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Authors: Frederik Heymann Lassen, Duncan S. Palmer
DOI: 10.5281/zenodo.18944246
Cited by: 0

Abstract

UK Biobank summary statistics from "Deviations from genetic additivity driven by rare variants at biobank scale" Summary statistics from genome-wide scans for nonadditive (dominance deviation) genetic effects across 2,906 plasma proteins and 55 quantitative traits in 399,943 UK Biobank individuals. Generated using an orthogonal allelic recoding framework that enables scalable testing of nonadditive effects without Hardy-Weinberg equilibrium assumptions, integrated with linear mixed models.

Fields of Study & Subjects

Genetic Associations and Epidemiology Genetic and phenotypic traits in livestock Genetic Mapping and Diversity in Plants and Animals

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
10 March 2026
Language
EN
Document type
Dataset