Single-nuclei transcriptomic profiling of human myocardium in long chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency

Single-nuclei transcriptomic profiling of human myocardium in long chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency Hanna J. Tadros MBBCh1, Diwakar Turaga MD, PhD2,3, Yi Zhao PhD6, Chang-Ru Tsai, PhD9, Lalita Wadhwa PhD4, Debra L. Kearney MD7, Iki Adachi MD4,5, Xiao Li PhD6,8, James F. Martin MD, PhD6,9,10* 1. Department of Pediatrics, Section of Pediatric Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA. 2. Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA 3. Division of Critical Care Medicine, Texas Children's Hospital, Houston TX, USA 4. Department of Surgery, Baylor College of Medicine, Houston, TX, USA 5. Division of Congenital Heart Surgery, Texas Children's Hospital, Houston, TX, USA 6. The Texas Heart Institute at Baylor College of Medicine, Houston, TX, USA 7. Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA 8. Department of Medicine, Baylor College of Medicine, Houston, TX, USA 9. Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA 10. Center for Organ Repair and Renewal, Baylor College of Medicine, Houston, TX, USA *Corresponding author. Email: jfmartin@bcm.edu