Development of 3D Printed Pharmaceutical Cocrystals

The project investigates the integration of pharmaceutical cocrystals into extrusion-based 3D printed solid dosage forms, aiming to improve the solubility, stability, and personalized delivery of drugs through tailored geometries and controlled release profiles. The research will generate experimental and computational datasets related to cocrystal screening and characterization (e.g., PXRD, DSC, TGA, FTIR, Raman), formulation and rheological properties, 3D printing process parameters, mechanical testing, dissolution and drug release studies, as well as simulation and structure–process–performance relationship data.The purpose of this DMP is to ensure that all project data are systematically collected, well documented, securely stored, and appropriately shared. Data management will follow FAIR principles (Findable, Accessible, Interoperable, and Reusable) to support transparency, reproducibility, and Open Science, enabling reuse of datasets by other researchers and industry stakeholders working in pharmaceutical 3D printing and cocrystal-based dosage forms. The Data Management Plan (DMP) is prepared in the framework of the Latvian Council of Science Fundamental and Applied Research project No. lzp-2025/1-0263 "Development of 3D Printed Pharmaceutical Cocrystals" (project manager: Dr. chem. Artis Kons, 01.01.2026. - 31.12.2028., 300 000.00 EUR).