What are the genetic variances in codeine pharmacodynamics and pharmacokinetics?

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Tripdatabase
DOI: 10.5281/zenodo.18991492
Cited by: 0

Abstract

Codeine's effects vary significantly due to genetic polymorphisms in CYP2D6, impacting efficacy and safety, prompting careful consideration in its use, especially in populations at risk of adverse effects.

Fields of Study & Subjects

Pharmacogenetics and Drug Metabolism Pain Management and Opioid Use Genetic Associations and Epidemiology

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
12 March 2026
Language
EN