Morphogen-Diffusion-Simulation-in-Extracellular-Space

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Authors: Thorsten Wohland
Cited by: 0

Abstract

Simulation of morphogen diffusion in channels with receptor binding. The code has been written im Mathematica 12.3 (Wolfram Research, Illinois, USA). All instructions are provided within the Mathematica file. When run it will provide as output a plot showing how the diffusion coefficient (im m^2/s) will change with distance (in m) given the user defined situation (channel width, binding and unbinding probbalities, diffusion coefficient in free space, number of particles, and simulation time steps and length). Simulations should be run long enough to converge. In the case provided in the file the simulations converges latest at 0.1 s; simulations are run over 2 s. An example output plot is given at the end of the file.

Fields of Study & Subjects

Developmental Biology and Gene Regulation Mathematical Biology Tumor Growth Gene Regulatory Network Analysis

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
13 March 2026
Language
EN