A RETROSPECTIVE ASSESMENT OF CLINICAL OUTCOMES ASSOCIATED WITH MULTI – DRUG REGIMEN APPROACHES IN PATIENTS WITH DIABETES MELLITUS

Diabetes mellitus is a chronic metabolic disorder requiring long-term pharmacological management to achieve optimal glycemic control and prevent complications. The present retrospective study aimed to assess the clinical outcomes associated with multi-drug regimen approaches in patients diagnosed with diabetes mellitus. Medical records of patients receiving combination pharmacotherapy over a defined period were reviewed to evaluate glycemic parameters, incidence of diabetes-related complications, hospitalization rates and medication adherence. The findings indicated that patients treated with multi-drug regimens demonstrated significant improvement in glycemic control, evidenced by reductions in fasting blood glucose and glycated haemoglobin (HbA1c) levels.However, increased pill burden and the potential risk of adverse drug reactions were noted in a subset of patients. Overall, the study highlights the clinical effectiveness of multi-drug regimen strategies in optimizing therapeutic outcomes among diabetic patients, while emphasizing the importance of individualized treatment planning, regular monitoring, and patient education to minimize complications and enhance adherence. Further prospective studies are recommended to validate these findings and establish standardized treatment protocols.